Caspase-8 Antibody AF705 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemCaspase-8 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberAF705
NCBI Gene AliasesALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5
ApplicationsWestern Blot, Simple Western
Conjugate/TagUnconjugated
ReactivityHuman, Mouse
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
IsotypeIgG
HostGoat
Quantity100 ug (also 25 ug)
TargetCaspase-8
NCBI Full Gene Namecaspase 8
ClonalityPolyclonal
ImmunogenE. coli-derived recombinant human Caspase-8, Ser234-Asp496, Accession # AAC50645
ConcentrationLYOPH
PurityAntigen Affinity-purified
Brand/TrademarkR&D Systems, a Bio-Techne Brand
ValidationKnockout Validated
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human and mouse Caspase-8 in Western blots

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Significance of calreticulin as a prognostic factor in endometrial cancerOncology LettersApril 13, 2018Qin Xu, Chuanben Chen, Guilin Chen, Wei Chen, Dongmei Zhou, Yunqing Xiedistant failure, and overall survival (OS). Reagents Primary antibodies against CRT (MAB3898), p-eIF2a (AF705) and PERK (AF3999) were purchased from R&D systems. Primary antibodies against Ki67 (ab15580), and β-Actin

(2) Contrasting roles of H3K4me3 and H3K9me3 in regulation of apoptosis and gemcitabine resistance in human pancreatic cancer cellsBMC cancerFebruary 6, 2018Lu C, Yang D, Sabbatini ME, Colby AH, Grinstaff MW, Oberlies NH, Pearce C, Liu K.Cell signaling technology 2933P WB CoxIV Cell signaling technology 4844 WB Cleaved caspase 8 R&D system AF705 WB Cleaved caspase 9 Cell signaling technology 9501S WB Cleaved caspase 3 Cell signaling technology 9661S WB Cleaved

(3) Saturated fatty acids activate caspase-4/5 in human monocytes, triggering IL-1β and IL-18 releaseAmerican Journal of Physiology-Endocrinology and MetabolismNovember 1, 2016Nicolas J. Pillon, Kenny L. Chan, Shitian Zhang, Marios Mejdani, Maya R. Jacobson, Alexandre Ducos, Philip J. Bilan, Wenyan Niu, Amira Klip(no. 4970, Lot 14, 1:5,000) were from Cell Signaling Technology (Beverly, MA). Caspase-8 antibody (AF705, Lot KIZ0110061, 1:1,000) from R&D systems (Minneapolis, MN). Alpha-actinin-1 (A5044, Lot 082M4794,

(4) Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reactionGenome biologySeptember 19, 2016Genshaft AS, Li S, Gallant CJ, Darmanis S, Prakadan SM, Ziegler CG, Lundberg M, Fredriksson S, Hong J, Regev A, et al.Permeabilize Buffer supplemented with 4 μg/ mL primary antibody (BIRC5: NB500-201, Novus Biologicals; CASP8: AF705, R&D Systems; ICAM1: AF720, R&D Systems; MKI67: ab15580, Abcam, Inc.) and incubated at 4 °C overnight.

(5) NF-κB functions as a molecular link between tumor cells and Th1/Tc1 T cells in the tumor microenvironment to exert radiation-mediated tumor suppressionOncotargetApril 26, 2016Priscilla S. Simon et al.analysis Western blotting analysis was performed as previously described [65]. Anti-cleaved caspase 8 (Cat#: AF705, 0.5μg/ml) and anti-cIAP1 (Cat#: AF8181, 1:500) were obtained from R&D systems. Anti-caspase 3 (Cat#:

(6) Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in miceThe Journal of clinical investigationAugust 1, 2010Murthy A, Defamie V, Smookler DS, Di Grappa MA, Horiuchi K, Federici M, Sibilia M, Blobel CP, Khokha R.

(7) Ellipticine derivative NSC 338258 represents a potential new antineoplastic agent for the treatment of multiple myelomaMolecular cancer therapeuticsMarch 1, 2008Tian E, Landowski TH, Stephens OW, Yaccoby S, Barlogie B, Shaughnessy JD Jr.

(8) The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta productionProceedings of the National Academy of Sciences of the United States of AmericaJune 27, 2006Chae JJ, Wood G, Masters SL, Richard K, Park G, Smith BJ, Kastner DL.

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Caspase-8 Antibody

Caspase-8 Antibody

Caspase-8 Antibody

Caspase-8 Antibody

Caspase-8 Antibody

Caspase-8 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

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Caspase-8 Antibody from R&D Systems, a Bio-Techne Brand

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